United States securities and exchange commission logo January 4, 2021 Dror Harats Chief Executive Officer Vascular Biogenics Ltd. 8 HaSatat St. Modi in Israel 7178106 Re: Vascular Biogenics Ltd. Registration Statement on Form F-3 Filed December 30, 2020 File No. 333-251821 Dear Mr. Harats: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Jason L. Drory at 202-551-8342 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Michael J. Rosenberg, Esq.